Glacios Microscopy Papers – Page 2

⭐ Foundational

Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.

PLoS biology 2021 📊 167

The recently reported "UK variant" (B.1.1.7) of SARS-CoV-2 is thought to be more infectious than previously circulating strains as a result of several changes, including...

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⭐ Foundational

De novo design of protein interactions with learned surface fingerprints.

Nature 2023 📊 221

AbstractPhysical interactions between proteins are essential for most biological processes governing life1. However, the molecular determinants of such interactions have been challenging to understand, even...

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⭐ Foundational

A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation.

Journal of extracellular vesicles 2022 📊 230

AbstractNanoparticles can acquire a plasma protein corona defining their biological identity. Corona functions were previously considered for cell‐derived extracellular vesicles (EVs). Here we demonstrate that...

Confocal Laser Scanning Microscopy Direct Stochastic Optical Reconstruction Microscopy Stochastic Optical Reconstruction Microscopy Super-Resolution Microscopy Transmission Electron Microscopy Axio Observer Glacios LSM 700 Observer 7 Ti Zeiss Lightsheet Z.1 Light Sheet Zeiss LSM 700 Confocal Homo sapiens NIS-Elements Alexa Fluor 488 Alexa Fluor 647 APC ATTO 488 BODIPY Calcein Calcein-AM Cy3 Cy7 FITC Cell Culture Fixation Glutaraldehyde Hematoxylin and Eosin Immunohistochemistry Primary Fibroblasts Primary Keratinocytes Primary Mesenchymal Stem Cells Primary Monocytes Primary Natural Killer Cells Primary T Cells Zeiss Lightsheet Z.1 Light Sheet Zeiss LSM 700 Confocal ImageJ SerialEM NIS-Elements GraphPad Prism R Lodron University Medical University Medical University of Vienna Pomeranian Medical University University of Vienna University Salzburg Abcam Agilent BD Biosciences Biotium Dako eBioscience Gibco ibidi Life Technologies Lonza Merck Millipore Promega Qiagen R&D Systems Roche Sigma-Aldrich Thermo Fisher Scientific VWR Thermo Fisher Falcon III

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⭐ Foundational

Hallucinating symmetric protein assemblies.

Science (New York, N.Y.) 2022 📊 225

Deep learning generative approaches provide an opportunity to broadly explore protein structure space beyond the sequences and structures of natural proteins. Here, we use deep...

Cryo-Electron Microscopy Negative Stain Electron Microscopy Glacios Escherichia coli ChimeraX UCSF Chimera Glacios ChimeraX UCSF Chimera Howard Hughes Medical Institute University of Washington

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⭐ Foundational

SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration.

Neuron 2021 📊 273

Axon degeneration is a central pathological feature of many neurodegenerative diseases. Sterile alpha and Toll/interleukin-1 receptor motif-containing 1 (SARM1) is a nicotinamide adenine dinucleotide (NAD+)-cleaving...

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Glacios

Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.

De novo design of protein interactions with learned surface fingerprints.

A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation.

Hallucinating symmetric protein assemblies.

SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration.

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