Observer 7

Observer 7

Microscope β€’ 55 papers

Spray inoculation and image analysis-based quantification of powdery mildew disease severity on pea leaves.

MethodsX 2024 πŸ“Š 6

Pea (Pisum sativum) is an important agricultural legume crop, but powdery mildew disease caused by the biotrophic fungus Erysiphe pisi regularly limits its annual yield....

Loss of surface transport is a main cellular pathomechanism of CRB2 variants causing podocytopathies.

Life science alliance 2023 πŸ“Š 6

Crumbs2 (CRB2) is a central component of the renal filtration barrier and part of the slit diaphragm, a unique cell contact formed by glomerular podocytes....

πŸ”₯ High Impact

Low micromolar concentrations of the superoxide probe MitoSOX uncouple neural mitochondria and inhibit complex IV.

Free radical biology & medicine 2015 πŸ“Š 83

MitoSOX Red is a fluorescent probe used for the detection of mitochondrial reactive oxygen species by live cell imaging. The lipophilic, positively charged triphenylphosphonium moiety...

πŸ”₯ High Impact

A diffusion-based neurite length-sensing mechanism involved in neuronal symmetry breaking.

Molecular systems biology 2010 πŸ“Š 84

Although there has been significant progress in understanding the molecular signals that change cell morphology, mechanisms that cells use to monitor their size and length...

πŸ”₯ High Impact

Effects of L-PRF and A-PRF+ on periodontal fibroblasts in in vitro wound healing experiments.

Journal of periodontal research 2020 πŸ“Š 85

OBJECTIVE: To determine whether leukocyte-platelet-rich fibrin (L-PRF) and advanced platelet-rich fibrin (A-PRF+) differ in their in vitro capacity to induce proliferation and migration of periodontal...

πŸ”₯ High Impact

Basic fibroblast growth factor elicits formation of interstitial axonal branches via enhanced severing of microtubules.

Molecular biology of the cell 2010 πŸ“Š 86

The formation of interstitial axonal branches involves the severing of microtubules at sites where new branches form. Here we wished to ascertain whether basic fibroblast...

⭐ Foundational

Spatiotemporal coordination of transcription preinitiation complex assembly in live cells.

Molecular cell 2021 πŸ“Š 122

Transcription initiation by RNA polymerase II (RNA Pol II) requires preinitiation complex (PIC) assembly at gene promoters. In the dynamic nucleus, where thousands of promoters...

πŸ’» Code πŸ’Ύ Data
⭐ Foundational

Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging.

Journal of the American Chemical Society 2015 πŸ“Š 133

Bioorthogonal reactions, including the strain-promoted azide-alkyne cycloaddition (SPAAC) and inverse electron demand Diels-Alder (iEDDA) reactions, have become increasingly popular for live-cell imaging applications. However, the...

⭐ Foundational

MuscleJ: a high-content analysis method to study skeletal muscle with a new Fiji tool.

Skeletal muscle 2018 πŸ“Š 135

BACKGROUND: Skeletal muscle has the capacity to adapt to environmental changes and regenerate upon injury. To study these processes, most experimental methods use quantification of...

⭐ Foundational

Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.

Cell 2019 πŸ“Š 135

The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) is the leading target for next-generation vaccines against the disease-causing blood-stage of malaria. However, little is known...

πŸ’Ύ Data 🏷️ 11 RRIDs

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