Direct Stochastic Optical Reconstruction Microscopy

Direct Stochastic Optical Reconstruction Microscopy

Technique • 652 papers

🔥 High Impact

Super-resolution imaging with Pontamine Fast Scarlet 4BS enables direct visualization of cellulose orientation and cell connection architecture in onion epidermis cells.

BMC plant biology 2013 📊 72

BACKGROUND: In plants, a complex cell wall protects cells and defines their shape. Cellulose fibrils form a multilayered network inside the cell-wall matrix that plays...

Extracellular vesicles from wild-type Epstein-Barr virus-transformed B-cells export host DNA and EBV EBER1.

bioRxiv : the preprint server for biology 2026

ABSTRACT Epstein–Barr virus (EBV) infection is nearly ubiquitous and strongly linked to multiple sclerosis (MS), but how EBV-infected B cells communicate with distal tissues remains...

Kinetic and Spatial Resolution by dSTORM of miniSOG-Mediated Proximity Labeling in Mammalian Cells.

Chembiochem : a European journal of chemical biology 2026

The mini Singlet Oxygen Generator (miniSOG) is a genetically encoded flavin-binding protein that enables photocatalytic proximity labeling upon blue-light illumination. Despite its widespread adoption for...

Imaging the Nanoscale Distribution of Phosphoinositides in the Cell Plasma Membrane with Single-Molecule Localization Super-Resolution Microscopy.

Methods in molecular biology (Clifton, N.J.) 2021

Phosphoinositides make up only a small fraction of cellular phospholipids yet control cell function in a fundamental manner. Through protein interactions, phosphoinositides define cellular organelle...

Latest trends in bioimaging and building a proactive network of early-career young scientists around bioimaging in Europe.

Biology open 2022

ABSTRACT Biological research is in constant need of new methodological developments to assess organization and functions at various scales ranging from whole organisms to interactions...

Nanoscale Fluorescent Characterizations and Origin Tracing of Extracellular Vesicles through Standard Preparation Methods.

ACS nano 2026

Extracellular vesicles (EVs) facilitate intercellular communication and have emerged as valuable diagnostic and prognostic biomarkers, therapeutic tools, and delivery systems. Due to their heterogeneity, precise...

Cell-Type-Specific Mechanical Thresholds of Piezo1 Regulate Cancer Cell Migration and Proliferation.

Analytical chemistry 2026

Piezo1 exhibits paradoxical roles in different malignancies, promoting metastasis in some contexts while suppressing tumor progression in others. This functional dichotomy significantly hampers its potential...

A Streamlined Protocol for Single-Molecule Localization Microscopy in Arabidopsis Nuclei.

Journal of visualized experiments : JoVE 2026

While confocal fluorescence microscopy has provided valuable insights into chromatin organization in plant nuclei, its diffraction-limited resolution constrains the investigation of chromatin architecture, motivating the...

🔥 High Impact

Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy.

ACS nano 2020 📊 87

Fluorescence lifetime imaging microscopy is an important technique that adds another dimension to intensity and color acquired by conventional microscopy. In particular, it allows for...

💾 Data
⭐ Foundational

Localization-based super-resolution imaging meets high-content screening.

Nature methods 2017 📊 109

Single-molecule localization microscopy techniques have proven to be essential tools for quantitatively monitoring biological processes at unprecedented spatial resolution. However, these techniques are very low...

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