Leica SP8 Confocal

Leica SP8 Confocal

Microscope • 248 papers

Spatial distribution and density of fibroblasts determine angiogenic response of endothelial cells.

Research square 2026

Abstract Fibroblasts play indispensable roles in orchestrating revascularization and angiogenesis of endothelial cells. However, it remains elusive the specific conditions under which the influence of...

Establishing Area-Specific Brain Organoids Through Transcription Factor-Mediated Patterning.

Biology 2026

The human cerebral cortex is organized into distinct area-specific regions along the rostral-caudal axis, yet current human brain organoid models incompletely recapitulate this regional diversity....

Route-Dependent Therapeutic Effects and Tissue Retention of Mesenchymal Stem Cell-Derived Exosomes in a Murine Model of Stevens-Johnson Syndrome.

Investigative ophthalmology & visual science 2026

PURPOSE: To test the therapeutic potential of mesenchymal stem cell-derived exosomes (MSC-exos) in ocular surface inflammation and to characterize immune responses in an IKAROS family...

An optimized confocal intravital microscopy protocol for long-term live imaging of murine F-actin organization during naïve lymphocyte migration.

STAR protocols 2021

Actin plays a crucial role during cell motility, but the organization of F-actin filaments during lymphocyte migration has not been visualized in vivo. Here, we...

[3D/4D strategic lymph node diagnostics : The 4D representation of the human lymph node enables the observation and interpretation of the immune system in space and time].

Pathologie (Heidelberg, Germany) 2023

BACKGROUND: Lymph-node diagnostics is performed using thin sections, with help of immunohistochemistry by light microscopy and supplemented by molecular pathology. OBJECTIVES: Which are the scientific...

Iron affects localization of Ght5 in fission yeast.

FEMS microbiology letters 2023

Abstract Iron is an essential cofactor for eukaryotic cells, as well as a toxic metal under certain conditions. On the other hand, glucose is the...

Preparation and application of fluorescent monoclonal antibodies recognizing goat CD4+CD25+ regulatory T cells.

Applied microbiology and biotechnology 2024

Abstract Regulatory T cells (Tregs) are a subset of T cells participating in a variety of diseases including mycoplasmal pneumonia, contagious ecthyma, and so on....

Post-transcriptional regulation of cyclin A and cyclin B mRNAs is mediated by Bruno 1 and Cup, and further fine-tuned within P-bodies.

bioRxiv : the preprint server for biology 2024

Abstract Cell cycle progression is tightly controlled by the regulated synthesis and degradation of Cyclins, such as Cyclin A and Cyclin B, which activate CDK1...

Analysis of Deposition and Diffusion of Cholesterol in Silicone Hydrogel Contact Lenses Using Confocal Microscopy.

Vision (Basel, Switzerland) 2024

In this study, we investigated lipid deposition and diffusion in silicone hydrogel (Si-Hy) contact lenses using confocal microscopy. Different Si-Hy lenses were analyzed to understand...

3D imaging and quantitative analysis of adipocytes in situ and ex situ.

Adipocyte 2025

Different adipose tissues (AT) have been described, including subcutaneous and visceral tissues (SCAT and VAT). They display different morphological structures, physiological and metabolic functions. Imaging...

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