Brightfield Microscopy

Brightfield Microscopy

Technique • 558 papers

🔥 High Impact

Therapeutic efficacy of different routes of mesenchymal stem cell administration in corneal injury.

The ocular surface 2019 📊 69

PURPOSE: Corneal injuries are associated with significant impairment in vision. Mesenchymal stem cells (MSCs) have been shown to limit inflammation and promote tissue repair at...

Machine Learning-Assisted Rapid Optical Imaging for Label-Free CAR T-Cell Detection in Whole Blood.

Biosensors 2026

Chimeric antigen receptor (CAR) T-cell therapy is an effective treatment for hematologic malignancies. However, it is limited by high costs, risk of severe toxicities such...

Comparing Deep Learning Performance for Chronic Lymphocytic Leukaemia Cell Segmentation in Brightfield Microscopy Images.

Bioinformatics and biology insights 2024

Objectives: This article focuses on the detection of cells in low-contrast brightfield microscopy images; in our case, it is chronic lymphocytic leukaemia cells. The automatic...

Deep Learning-Based Imaging Analysis Reveals Radiation-Induced Bystander Effects on Cancer Cell Migration and the Modulation by Cisplatin.

International journal of molecular sciences 2025

Regulating tumor invasion and metastasis is pivotal for improving cancer patient prognosis. While cell migration is a key factor in these processes, the non-targeted effects...

Fluorescent marker prediction for non-invasive optical imaging in bovine satellite cells using deep learning.

Frontiers in artificial intelligence 2025

Assessing the quality of bovine satellite cells (BSCs) is vital for advancing tissue engineered muscle constructs with applications in sustainable protein research. In this study,...

Deep-learning-based automated prediction of mouse seminiferous tubule stage by using bright-field microscopy.

Scientific reports 2025

Infertility is a global issue, and approximately 50% of cases are due to male factors, with defective spermatogenesis being the main one. For studies of...

💾 Data

Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis.

Frontiers in pharmacology 2025

Background Sepsis is a life-threatening condition characterized by organ dysfunction resulting from a dysregulated host response to infection. Sepsis induces systemic inflammation and increases adhesion...

Dual-mode multichannel imaging system for high-throughput live-cell monitoring across large fields of view.

Journal of biomedical optics 2025

SIGNIFICANCE: High-throughput live-cell imaging is crucial for biological applications, including organ-on-a-chip (OoaC) platforms, yet conventional optical systems face a fundamental trade-off between magnification and field...

Analysis of target mRNAs in the fixed-frozen human brain using a modified BaseScope-ISH Assay protocol.

STAR protocols 2022

We describe a modified BaseScope™ Assay protocol (ACDBio) for RNA in situ hybridization on fixed-frozen human brain tissue. The original protocol caused tissue detachment due to...

Generation, culture, and stimulation of small intestinal murine organoids in parasitology research.

STAR protocols 2023

Parasitic helminth worms frequently infect the gastrointestinal tract and interact with the intestinal epithelium and specialized cell types within it. Intestinal organoids derived from stem...

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