Leica SP5 Confocal

Leica SP5 Confocal

Microscope • 293 papers

🔥 High Impact

Therapeutic efficacy of different routes of mesenchymal stem cell administration in corneal injury.

The ocular surface 2019 📊 69

PURPOSE: Corneal injuries are associated with significant impairment in vision. Mesenchymal stem cells (MSCs) have been shown to limit inflammation and promote tissue repair at...

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COPI selectively drives maturation of the early Golgi.

eLife 2015 📊 69

COPI coated vesicles carry material between Golgi compartments, but the role of COPI in the secretory pathway has been ambiguous. Previous studies of thermosensitive yeast...

📋 38 💾 Data
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Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis.

Gut 2022 📊 69

Objective Bleeding ulcers and erosions are hallmarks of active ulcerative colitis (UC). However, the mechanisms controlling bleeding and mucosal haemostasis remain elusive. Design We used...

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Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling.

Cell reports 2019 📊 69

Adaptor protein 2 (AP2) is a major constituent of clathrin-coated pits (CCPs). Whether it is essential for all forms of clathrin-mediated endocytosis (CME) in mammalian...

🏷️ 16 RRIDs
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TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells.

Cell calcium 2013 📊 70

Cell migration depends on the dynamic formation and turnover of cell adhesions and is tightly controlled by actomyosin contractility and local Ca2+ signals. The divalent...

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The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

Nature communications 2011 📊 71

Deubiquitinating enzymes are now emerging as potential therapeutic targets that control many cellular processes, but few have been demonstrated to control cell motility. Here, we...

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Super-resolution imaging with Pontamine Fast Scarlet 4BS enables direct visualization of cellulose orientation and cell connection architecture in onion epidermis cells.

BMC plant biology 2013 📊 72

BACKGROUND: In plants, a complex cell wall protects cells and defines their shape. Cellulose fibrils form a multilayered network inside the cell-wall matrix that plays...

Discrete protein metric (DPM): A new image similarity metric to calculate accuracy of deep learning-generated cell focal adhesion predictions.

Micron (Oxford, England : 1993) 2022

Understanding cell behaviors can provide new knowledge on the development of different pathologies. Focal adhesion (FA) sites are important sub-cellular structures that are involved in...

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Enhanced Visualisation of Colorectal Tumours via Topical Application of EMI-137 in a Methylcellulose-Based Formulation: An ex vivo Feasibility Study.

Molecular imaging and biology 2025

Abstract Background Fluorescence-guided molecular imaging may improve colorectal cancer (CRC) patient outcomes by enabling early detection and better surgical treatment, relying on developing targeted fluorescent...

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