Technique • 2854 papers
The visualization of whole organs and organisms through tissue clearing and fluorescence volumetric imaging has revolutionized the way we look at biological samples. Its application to...
Ca 2+ signaling and its regulation are important for endothelial cell (EC) function and signaling. Yet, the spatiotemporal organization of Ca 2+ activity and its...
Introduction Molybdenum (Mo) is a potential biodegradable stent material that has excellent mechanical and degradation properties. Recent studies suggest that chronic exposure to Mo is...
Abstract Background Perivascular spaces (PVS) contribute to brain clearance, as they connect the cerebrospinal fluid (CSF) in the subarachnoid space and ventricular system with the...
Intravital imaging with conventional microscopy faces major technical barriers, including limited spatial resolution, high background noise, and motion artifacts caused by physiological activity such as...
Abstract Understanding how neurons integrate synaptic inputs requires imaging techniques capable of capturing rapid, three-dimensional dendritic events. These processes occur on millisecond timescales and submicron...
Photonic imaging technologies have profoundly transformed neuro-ophthalmic diagnostics by enabling non-invasive visualization of neurodegenerative processes at the retinal level. This review examines how advanced light-based...
Wide-field temporal focused (WF-TeFo) two-photon microscopy allows for the simultaneous imaging of a large planar area, with a potential order of magnitude enhancement in the...
Abstract Several midbrain nuclei degenerate in Parkinson’s Disease (PD). Many of these nuclei share the common characteristics that are thought to contribute to their selective...
Fluorescence lifetime imaging microscopy (FLIM) has proven to be a useful method for analyzing various aspects of material science and biology, like the supramolecular organization...