Nikon Ti2

Nikon Ti2

Microscope • 93 papers

⭐ Foundational

Structure and dynamics of the EGFR/HER2 heterodimer.

Cell discovery 2023 📊 117

Abstract HER2 belongs to the human epidermal growth factor receptor tyrosine kinase family. Its overexpression or hyperactivation is a leading cause for multiple types of...

Confocal Laser Scanning MicroscopyCryo-Electron MicroscopyLive Cell ImagingSingle-Molecule ImagingSpinning Disk Confocal MicroscopyTotal Internal Reflection Fluorescence MicroscopyZ-Stack ImagingNikon Ti2Yokogawa CSU-X1 Spinning DiskDrosophila melanogasterEscherichia coliMicroManagerAlexa Fluor 488GFPmCherrymEGFPmScarletCell CultureClustered Regularly Interspaced Short Palindromic RepeatsFixationKnockdownKnockoutLipofectionLive ImagingTransductionTransfectionEmbryonic Stem CellHuman Breast Carcinoma SK-BR-3Human Embryonic Kidney 293Yokogawa CSU-X1 Spinning DiskChimeraXcryoSPARCDigital MicrographRELIONSerialEMTrackMateMicroManagerMATLABChinese Academy of SciencesPeking UniversityState Key Laboratory of Membrane BiologyState Key Laboratory of Molecular Developmental BiologyUniversity of Chinese Academy of SciencesAbcamAddgeneBD BiosciencesCell Signaling TechnologyCorningCytivaGibcoInvitrogenLife TechnologiesSigma-AldrichGoatMouseCoherent OBIS 488diodeAndor EMCCDAndor iXon Life 888Andor iXon Ultra 897Hamamatsu EMCCDPhotometrics Evolve 512Yokogawa EMCCDNikon Apochromat TIRF 100×
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⭐ Foundational

Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis.

eLife 2020 📊 129

Force generation by actin assembly shapes cellular membranes. An experimentally constrained multiscale model shows that a minimal branched actin network is sufficient to internalize endocytic...

Atomic Force MicroscopyConfocal Laser Scanning MicroscopyCryo-Electron TomographyElectron TomographyLive Cell ImagingSpinning Disk Confocal MicroscopyTotal Internal Reflection Fluorescence MicroscopyNikon TiNikon Ti2TiTi2TitanEscherichia coliHomo sapiensMetaMorphCF680DiDEGFPGFPPhalloidinRFPsfGFPTagRFPTagRFP-TYFPCell CultureElectroporationFixationKnockdownLipofectionTransfectionHeLa (Henrietta Lacks)NIH 3T3 Mouse FibroblastTiTi2TitanDigital MicrographIMODSerialEMTrackMateMetaMorphMATLABPythonUniversity of CaliforniaCorningGibcoLonzaQiagenSigma-AldrichTakara BioVWRDonkeyMouseRabbitAndor EMCCDAndor iXonEMCCDHamamatsu Orca Flash 4.0Hamamatsu sCMOSsCMOS100x/1.45 NANikon 60x/1.49 NA
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⭐ Foundational

A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics.

eLife 2020 📊 148

We present an oblique plane microscope (OPM) that uses a bespoke glass-tipped tertiary objective to improve the resolution, field of view, and usability over previous...

Confocal Laser Scanning MicroscopyDeconvolution MicroscopyFluorescence Recovery After PhotobleachingLattice Light Sheet MicroscopyLight Sheet Fluorescence MicroscopyOptical SectioningOptogeneticsWidefield Fluorescence MicroscopyZ-Stack ImagingNikon Ti2TiTi2TitanDrosophila melanogasterMicroManagerDAPIEGFPGCaMP6fGFPmCherrymNeonGreenmScarletmVenusRFPTRITCCell CultureClustered Regularly Interspaced Short Palindromic RepeatsCryosectioningFixationFluorescence In Situ HybridizationImmunostainingIn Situ HybridizationLentiviralLipofectionLive ImagingParaformaldehyde FixationTransductionTransfectionVibratomeHuman Chronic Myelogenous Leukemia K562Human Embryonic Kidney 293Human Embryonic Kidney 293THuman Osteosarcoma U2OSMouse Embryonic FibroblastPrimary CardiomyocytesPrimary Mesenchymal Stem CellsPrimary Natural Killer CellsPrimary NeuronsPrimary T CellsTiTi2TitanBigDataViewerFijiImarisIMODMicroManagerLabVIEWMATLABPythonRArizona State UniversityBaylor College of MedicineBaylor College of Medicine and Texas Children's HospitalCalico Life SciencesDuke UniversityHarold C. Simmons Comprehensive Cancer CenterMichigan State Universitys HospitalState UniversityUniversity of ChileUniversity of QueenslandUniversity of Texas Southwestern Medical CenterUniversity School of MedicineAddgeneBio-RadCorningGibcoibidiInvitrogenLonzaMatTekMilliporeNew England BiolabsRocheSigma-AldrichTakara BioThermo Fisher ScientificDonkeyRabbitRatHamamatsu sCMOSPhotometrics Prime BSIPhotometrics Prime BSI ExpressPhotometrics sCMOSsCMOSApo 25XApo Lambda 40XSemrock Di02-R488Semrock Di03-R405ZET405/488
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