Ovis aries

Ovis aries

Organism β€’ 21 papers

⭐ Foundational

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation.

Nucleic acids research 2007 πŸ“Š 258

Postreplicative maintenance of genomic methylation patterns was proposed to depend largely on the binding of DNA methyltransferase 1 (Dnmt1) to PCNA, a core component of...

A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion.

bioRxiv : the preprint server for biology 2024 πŸ“Š 1

ABSTRACT Pasteurella multocida is the leading cause of wound infections in humans following animals’ bites or scratches. This bacterium is also commonly found in the...

πŸ’Ύ Data

Cryo-EM structure of the brine shrimp mitochondrial ATP synthase suggests an inactivation mechanism for the ATP synthase leak channel.

Cell death and differentiation 2025 πŸ“Š 6

Abstract Mammalian mitochondria undergo Ca2+-induced and cyclosporinA (CsA)-regulated permeability transition (mPT) by activating the mitochondrial permeability transition pore (mPTP) situated in mitochondrial inner membranes. Ca2+-induced...

πŸ’Ύ Data 🏷️ 2 RRIDs

Structural basis for non-AUG translation regulation by 5MPs.

bioRxiv : the preprint server for biology 2025 πŸ“Š 4

Abstract The cellular proteome is regulated by translation initiation on AUG or non-canonical (non-AUG) start codons 1–3 . Non-AUG initiation remodels proteome during stress and...

πŸ’» Code πŸ’Ύ Data

Point Mutations of Nicotinic Receptor Ξ±1 Subunit Reveal New Molecular Features of G153S Slow-Channel Myasthenia.

Molecules (Basel, Switzerland) 2021 πŸ“Š 2

Slow-channel congenital myasthenic syndromes (SCCMSs) are rare genetic diseases caused by mutations in muscle nicotinic acetylcholine receptor (nAChR) subunits. Most of the known SCCMS-associated mutations...

πŸ’Ύ Data

A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion.

PLoS pathogens 2025 πŸ“Š 2

Pasteurella multocida is the leading cause of wound infections in humans following animals' bites or scratches. This bacterium is also commonly found in the respiratory...

πŸ’Ύ Data

Engineering of a mammalian VMAT2 for cryo-EM analysis results in non-canonical protein folding.

Nature communications 2024 πŸ“Š 3

AbstractVesicular monoamine transporter 2 (VMAT2) belongs to the major facilitator superfamily (MFS), and mediates cytoplasmic monoamine packaging into presynaptic vesicles. Here, we present two cryo-EM...

πŸ’Ύ Data

Using cryo-EM to understand the assembly pathway of respiratory complex I.

Acta crystallographica. Section D, Structural biology 2024 πŸ“Š 4

Complex I (proton-pumping NADH:ubiquinone oxidoreductase) is the first component of the mitochondrial respiratory chain. In recent years, high-resolution cryo-EM studies of complex I from various...

πŸ’Ύ Data

Structures of native SV2A reveal the binding mode for tetanus neurotoxin and anti-epileptic racetams.

Nature communications 2025 πŸ“Š 4

The synaptic vesicle glycoprotein 2A (SV2A) is a synaptic vesicle (SV) resident with homology to the major facilitator superfamily (MFS) and essential in vertebrate neurotransmission....

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The plate body: 3D ultrastructure of a facultative organelle of alveolar epithelial type II cells involved in SP-A trafficking.

Histochemistry and cell biology 2021 πŸ“Š 5

AbstractPlate bodies are facultative organelles occasionally described in the adult lungs of various species, including sheep and goat. They consist of multiple layers of plate-like...

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