Technique • 1935 papers
Abstract Cell cycle progression is tightly controlled by the regulated synthesis and degradation of Cyclins, such as Cyclin A and Cyclin B, which activate CDK1...
Abstract From molecules to organelles, cells exhibit recurring structural motifs across multiple scales. Understanding these structures provides insights into their functional roles. While super-resolution microscopy...
PURPOSE: To characterize the distribution of reticular fibers in the human sclera and explore their potential role in the pathogenesis of pathologic myopia and posterior...
SIGNIFICANCE: Prostate biopsy remains the gold standard for prostate cancer (PCa) diagnosis and treatment planning. However, current techniques suffer from low cancer detection rates, with...
Abstract Mesoscale neuronal networks represent an intermediate organizational level linking single-neuron activity to large-scale brain networks. Here, we used in vivo two-photon calcium imaging and...
Abstract Background The roles of p53 and HER2 in gastric adenocarcinoma (GAC) have been extensively studied; nevertheless, the contribution of mitochondrial transcription factor A (TFAM)...
INTRODUCTION: Epithelial sodium channel (ENaC) is a major conduit for sodium transport across the cell membrane, and its activity is regulated by multiple factors/mechanisms, including...
Abstract Eukaryotic chromosome segregation requires spindle microtubules to attach to chromosomes through kinetochores. The chromosomal locus that mediates kinetochore assembly is the centromere and is...
Eukaryotic cells follow a conserved cell cycle that regulates diverse processes, including DNA maintenance and organelle homeostasis. Studying cellular processes in a cell cycle-dependent manner...
ABSTRACT Conventional analytical methods for fluorescence lifetime imaging (FLI) require the instrument response function (IRF) alongside temporal fluorescence decay to accurately estimate lifetime parameters. While...