Axiovert

Axiovert

Microscope â€Ē 138 papers

ðŸ”Ĩ High Impact

Basic fibroblast growth factor elicits formation of interstitial axonal branches via enhanced severing of microtubules.

Molecular biology of the cell 2010 📊 86

The formation of interstitial axonal branches involves the severing of microtubules at sites where new branches form. Here we wished to ascertain whether basic fibroblast...

ðŸ”Ĩ High Impact

Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells.

Hepatology (Baltimore, Md.) 2011 📊 86

Abstract Here we demonstrate that primary cultures of human fetal liver cells (HFLC) reliably support infection with laboratory strains of hepatitis C virus (HCV), although...

ðŸ”Ĩ High Impact

Cell models of lipid-rich Îą-synuclein aggregation validate known modifiers of Îą-synuclein biology and identify stearoyl-CoA desaturase.

Proceedings of the National Academy of Sciences of the United States of America 2019 📊 87

Microscopy of Lewy bodies in Parkinson's disease (PD) suggests they are not solely filamentous deposits of Îą-synuclein (ÎąS) but also contain vesicles and other membranous...

ðŸ’ŧ Code ðŸ’ū Data
⭐ Foundational

Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection.

PloS one 2017 📊 122

The non-pathogenic parvovirus, adeno-associated virus (AAV), is an efficient vector for transgene expression in vivo and shows promise for treatment of brain disorders in clinical...

⭐ Foundational

Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly.

The Journal of cell biology 2011 📊 123

During mitosis, the nuclear envelope merges with the endoplasmic reticulum (ER), and nuclear pore complexes are disassembled. In a current model for reassembly after mitosis,...

⭐ Foundational

Miro1-dependent mitochondrial positioning drives the rescaling of presynaptic Ca2+ signals during homeostatic plasticity.

EMBO reports 2017 📊 124

Abstract Mitochondrial trafficking is influenced by neuronal activity, but it remains unclear how mitochondrial positioning influences neuronal transmission and plasticity. Here, we use live cell...

ðŸ’ū Data
⭐ Foundational

Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes.

Journal of cell science 2008 📊 124

The biological function of receptors is determined by their appropriate trafficking through the endosomal pathway. Following internalization, the transferrin (Tf) receptor quantitatively recycles to the...

⭐ Foundational

Live cell imaging of repetitive DNA sequences via GFP-tagged polydactyl zinc finger proteins.

Nucleic acids research 2007 📊 125

Several techniques are available to study chromosomes or chromosomal domains in nuclei of chemically fixed or living cells. Current methods to detect DNA sequences in...

⭐ Foundational

Live cell imaging of germination and outgrowth of individual bacillus subtilis spores; the effect of heat stress quantitatively analyzed with SporeTracker.

PloS one 2013 📊 125

Spore-forming bacteria are a special problem for the food industry as some of them are able to survive preservation processes. Bacillus spp. spores can remain...

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