Microscope • 179 papers
AbstractSynaptic plasticity is a fundamental feature of the CNS that controls the magnitude of signal transmission between communicating cells. Many electrical synapses exhibit substantial plasticity...
Somatostatin (SST) neurons in the suprachiasmatic nucleus (SCN) regulate circadian rhythms, yet their role in chronic sleep deprivation (cSD)-induced mood dysregulation is unclear. Our study...
SUMMARY The insular cortex (insula) is an interoceptive hub, which senses internal states such as hunger, thirst, pain, and emotions. Previous studies suggest that the...
A common problem in confocal microscopy is the decrease in intensity of excitation light and emission signal from fluorophores as they travel through 3D specimens,...
BACKGROUND: Dysregulation in neural circuits that encode arousal responses to aversive stimuli is thought to contribute to changes in motivated behaviors associated with neuropsychiatric disorders....
The creation of patient-derived cancer organoids represents a key advance in preclinical modeling and has recently been applied to a variety of human solid tumor...
AbstractInvestigating native human cardiac tissue with preserved 3D macro- and microarchitecture is fundamental for clinical and basic research. Unfortunately, the low accessibility of the human...
AbstractThe odor space of aquatic organisms is by necessity quite different from that of air-breathing animals. The recognized odor classes in teleost fish include amino...
Organ-on-chips and scaffolds for tissue engineering are vital assay tools for pre-clinical testing and prediction of human response to drugs and toxins, while providing an...
Abstract Background Cytokinins are a class of phytohormone that play a crucial role in the development of plants. They are involved in the regulation of...