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Microscope • 6 papers

Revealing the MRI-Contrast in Optically Cleared Brains.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024

AbstractThe current consensus holds that optically‐cleared specimens are unsuitable for Magnetic Resonance Imaging (MRI); exhibiting absence of contrast. Prior studies combined MRI with tissue‐clearing techniques...

Seizures drive tau propagation in a tauopathy mouse model.

bioRxiv : the preprint server for biology 2026

Abstract A bidirectional relationship between seizures and neurodegenerative disease has been established with neurodegenerative pathology found in late-onset epilepsy patients, increased risk of seizures in...

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Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope.

Nature 2023 📊 82

AbstractVisceral sensory pathways mediate homeostatic reflexes, the dysfunction of which leads to many neurological disorders1. The Bezold–Jarisch reflex (BJR), first described2,3 in 1867, is a...

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Aging drives cerebrovascular network remodeling and functional changes in the mouse brain.

Nature communications 2024 📊 71

Abstract Aging is frequently associated with compromised cerebrovasculature and pericytes. However, we do not know how normal aging differentially impacts vascular structure and function in...

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Shared and Distinct Brain Regions Targeted for Immediate Early Gene Expression by Ketamine and Psilocybin.

ACS chemical neuroscience 2023 📊 126

Psilocybin is a psychedelic with therapeutic potential. While there is growing evidence that psilocybin exerts its beneficial effects through enhancing neural plasticity, the exact brain...

💾 Data 🏷️ 1 RRID
⭐ Foundational

Autism genes converge on asynchronous development of shared neuron classes.

Nature 2022 📊 340

Genetic risk for autism spectrum disorder (ASD) is associated with hundreds of genes spanning a wide range of biological functions1-6. The alterations in the human brain...

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