Technique • 596 papers
Abstract Spatial transcriptomics and in situ hybridisation techniques have become essential for contextualising single‐cell RNA sequencing (scRNA‐seq) data by mapping cell type– and state–specific mRNA...
Objectives: The study aims to investigate the effects of laser-activated irrigation on infiltration and microleakage of a dual-curing resin cement applied as a root canal...
Abstract The nucleus of the solitary tract (NTS) and the area postrema (AP) form a tightly coupled dorsal medullary complex that integrates visceral and humoral...
BACKGROUND: Genome sequencing of a pedigree with familial ventricular fibrillation identified an ultrarare missense variant, p.R534S, in the DENND3 gene. DENND3 is a guanine nucleotide...
Cancer's notorious heterogeneity poses significant challenges, as each tumor comprises a unique ecosystem. While single-cell and spatial transcriptomics advancements have transformed our understanding of spatial...
The actin cytoskeleton plays multiple critical roles in cells, from cell migration to organelle dynamics. The small and transient actin structures regulating organelle dynamics are...
Imaging (fluorescence in situ hybridization [FISH]) and genome-wide chromosome conformation capture (Hi-C) are two major approaches to the study of higher-order genome organization in the...
Abstract Biocompatible fluorescent reporters with spectral properties spanning the entire visible spectrum are indispensable tools for imaging the biochemistry of living cells and organisms in...
Axons in the adult mammalian central nervous system fail to regenerate after spinal cord injury. Neurons lose their capacity to regenerate during development, but the...