Organism • 155 papers
Chagas disease, caused by the parasite Trypanosoma cruzi , affects millions of people globally. Unfortunately, the available treatment options, especially for the chronic stage of...
Abstract Membrane proteins are fundamental to many crucial cellular processes but removing them from their native environment for structural and functional studies creates experimental challenges....
Fractal analysis (FA) of neutrophils has demonstrated potential in identifying changes in chromatin associated with clinical parameters in individuals with chronic diseases. Therefore, this study...
Pentatricopeptide repeat (PPR) proteins constitute the largest family of RNA-binding proteins in land plants, playing crucial roles in organellar gene expression through sequence-specific RNA recognition....
AbstractTrypanosoma brucei is a model trypanosomatid, an important group of human, animal and plant unicellular parasites. Understanding their complex cell architecture and life cycle is challenging...
Endocytosis occurs at the cell surface and involves internalization of the plasma membrane (PM) along with its constituent membrane proteins and lipids. Endocytosis is involved...
The assembly and physiological function of cilia and flagella depend on the stable association of A- and B-tubules, which form axonemal doublet microtubules (DMTs). However,...
Trypanosoma brucei is the causal agent of African trypanosomiasis in humans and animals, the latter resulting in significant negative economic impacts in afflicted areas of...
Phosphagen kinases are vital for energy buffering and ATP regeneration in cells with high or fluctuating energy demands. Phosphagens are small, high-energy phosphate-storage molecules, such...
Expansion Microscopy (ExM) is a powerful method that enables super-resolution fluorescence microscopy, beyond the diffraction limit of light, with conventional fluorescence microscopes. Briefly, macromolecules of...