Community mesoSPIM Light Sheet

Community mesoSPIM Light Sheet

Microscope • 4 papers

🔥 High Impact

A guidebook for DISCO tissue clearing.

Molecular systems biology 2021 📊 80

Abstract Histological analysis of biological tissues by mechanical sectioning is significantly time‐consuming and error‐prone due to loss of important information during sample slicing. In the...

🔥 High Impact

Tutorial: practical considerations for tissue clearing and imaging.

Nature protocols 2021 📊 84

Tissue clearing has become a powerful technique for studying anatomy and morphology at scales ranging from entire organisms to subcellular features. With the recent proliferation...

⭐ Foundational

Neuroinflammation-Associated Aspecific Manipulation of Mouse Predator Fear by Toxoplasma gondii.

Cell reports 2020 📊 120

In rodents, the decrease of felid aversion induced by Toxoplasma gondii, a phenomenon termed fatal attraction, is interpreted as an adaptive manipulation by the neurotropic protozoan...

💾 Data
⭐ Foundational

The mesoSPIM initiative: open-source light-sheet microscopes for imaging cleared tissue.

Nature methods 2019 📊 282

Light-sheet microscopy is an ideal technique for imaging large cleared samples; however, the community is still lacking instruments capable of producing volumetric images of centimeter-sized...

💾 Data

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