Clarifying Tissue Clearing.
Biological specimens are intrinsically three dimensional; however, because of the obscuring effects of light scatter, imaging deep into a tissue volume is problematic. Although efforts...
iSPIM
iSPIM
Microscope • 38 papers
LiveLattice: Real-time visualization of tilted light-sheet microscopy data using a memory-efficient transformation algorithm.
ABSTRACT Light-sheet fluorescence microscopy (LSFM), a prominent fluorescence microscopy technique, offers enhanced temporal resolution for imaging biological samples in four dimensions (4D; x, y, z,...
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Homographically generated light sheets for the microscopy of large specimens.
We compare the performance of linear and nonlinear methods for aligning the excitation and detection planes throughout volumes of large specimens in digitally scanned light...
High activity and high functional connectivity are mutually exclusive in resting state zebrafish and human brains.
Abstract Background The structural connectivity of neurons in the brain allows active neurons to impact the physiology of target neuron types with which they are...
A 3D spheroid model for assessing nanocarrier-based drug delivery to solid tumors.
Abstract 3D spheroid culture has emerged as a valuable tool for studying complex intratumoral processes and screening novel therapeutics in vitro. However, spheroids face reproducibility...
LiveLattice: Real-time visualisation of tilted light-sheet microscopy data using a memory-efficient transformation algorithm.
Abstract Light‐sheet fluorescence microscopy (LSFM), a prominent fluorescence microscopy technique, offers enhanced temporal resolution for imaging biological samples in four dimensions (4D; x , y...
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💾 Data
Tissue dynamics spectroscopic imaging: functional imaging of heterogeneous cancer tissue.
SIGNIFICANCE: Tumor heterogeneity poses a challenge for the chemotherapeutic treatment of cancer. Tissue dynamics spectroscopy captures dynamic contrast and can capture the response of living...
Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection.
The world has seen the emergence of a new virus in 2019, SARS-CoV-2, causing the COVID-19 pandemic and millions of deaths worldwide. Microscopy can be...
A practical guide to light-sheet microscopy for nanoscale imaging: Looking beyond the cell.
We present a comprehensive guide to light-sheet microscopy (LSM) to assist scientists in navigating the practical implementation of this microscopy technique. Emphasizing the applicability of...
Assessment of photoacoustic tomography contrast for breast tissue imaging using 3D correlative virtual histology.
AbstractCurrent breast tumor margin detection methods are destructive, time-consuming, and result in significant reoperative rates. Dual-modality photoacoustic tomography (PAT) and ultrasound has the potential to...