ctASLM

ctASLM

Microscope • 7 papers

Universal consensus 3D segmentation of cells from 2D segmented stacks.

Nature methods 2025 📊 2

Abstract Cell segmentation is the foundation of a wide range of microscopy-based biological studies. Deep learning has revolutionized two-dimensional (2D) cell segmentation, enabling generalized solutions...

💻 Code 💾 Data

Universal consensus 3D segmentation of cells from 2D segmented stacks.

bioRxiv : the preprint server for biology 2025 📊 7

Cell segmentation is the foundation of a wide range of microscopy-based biological studies. Deep learning has revolutionized 2D cell segmentation, enabling generalized solutions across cell...

💻 Code 💾 Data
🔥 High Impact

Isotropic imaging across spatial scales with axially swept light-sheet microscopy.

Nature protocols 2022 📊 51

Light-sheet fluorescence microscopy is a rapidly growing technique that has gained tremendous popularity in the life sciences owing to its high-spatiotemporal resolution and gentle, non-phototoxic...

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🔥 High Impact

A guidebook for DISCO tissue clearing.

Molecular systems biology 2021 📊 80

Abstract Histological analysis of biological tissues by mechanical sectioning is significantly time‐consuming and error‐prone due to loss of important information during sample slicing. In the...

⭐ Foundational

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution.

Nature methods 2019 📊 162

We present cleared-tissue axially swept light-sheet microscopy (ctASLM), which enables isotropic, subcellular resolution imaging with high optical sectioning capability and a large field of view...

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