Leica DM6

Leica DM6

Microscope • 26 papers

Glioblastoma In Vitro Model That Recapitulates the Influence of the Hyaluronan Molecular Weight in Cancer Cell Motility and Permeability of the Blood-Brain Tumor Barrier.

ACS biomaterials science & engineering 2026

We report a glioblastoma (GBM) in vitro model that combines an extracellular matrix (ECM)-mimicking hydrogel, hyaluronan (HA), GBM spheroids, and a blood-brain barrier (BBB) component....

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Investigating the microstructure of plant leaves in 3D with lab-based X-ray computed tomography.

Plant methods 2018 📊 65

BACKGROUND: Leaf cellular architecture plays an important role in setting limits for carbon assimilation and, thus, photosynthetic performance. However, the low density, fine structure, and...

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Sequence-specific recognition of DNA minor groove by an NIR-fluorescence switch-on probe and its potential applications.

Nucleic acids research 2015 📊 67

In molecular biology, understanding the functional and structural aspects of DNA requires sequence-specific DNA binding probes. Especially, sequence-specific fluorescence probes offer the advantage of real-time...

Neural basis of collective social behavior during environmental challenge.

bioRxiv : the preprint server for biology 2024 📊 5

ABSTRACT Humans and animals have a remarkable capacity to collectively coordinate their behavior to respond to environmental challenges. However, the underlying neurobiology remains poorly understood....

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Acute intermittent hypoxia enhances nucleus of the solitary tract neuronal activity and requires NMDARs and CaMKII for phrenic long-term facilitation.

Journal of neurophysiology 2025

Exposure to acute intermittent hypoxia (AIH) induces phrenic long-term facilitation (pLTF). We have shown that nucleus tractus solitarii (nTS) activity is necessary for both the...

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A comprehensive toolkit for protein localization and functional analysis in trypanosomatids.

Open biology 2025 📊 3

African trypanosomes are medically important parasites that cause sleeping sickness in humans and nagana in animals. In addition to their pathogenic role, they have emerged...

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The rheology and foamability of crystal-melt suspensions composed of triacylglycerols.

Soft matter 2022 📊 4

The rheology of triacylglycerol (TAG) crystal-melt suspensions (CMSs) consisting of anhydrous milk fat (AMF), cocoa butter (CB), and palm kernel oil (PKO) as function of...

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Nature communications 2024 📊 4

The formation of new ribosomes is tightly coordinated with cell growth and proliferation. In eukaryotes, the correct assembly of all ribosomal proteins and RNAs follows...

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Protocol for determining the average speed and frequency of kinesin and dynein-driven intraflagellar transport (IFT) in C. elegans.

STAR protocols 2022 📊 4

Here, we present a protocol to image a fluorescent-labeled intraflagellar transport (IFT) component in Caenorhabditis elegans with fluorescence microscopy, including steps of sample preparations, in...

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Structural insight into transmissive mutant huntingtin species by correlative light and electron microscopy and cryo-electron tomography.

Biochemical and biophysical research communications 2021 📊 5

Aggregates of mutant huntingtin (mHTT) containing an expanded polyglutamine (polyQ) tract are hallmarks of Huntington's Disease (HD). Studies have shown that mHTT can spread between...

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