Nikon Ti

Nikon Ti

Microscope β€’ 353 papers

⭐ Foundational

Single-molecule displacement mapping unveils nanoscale heterogeneities in intracellular diffusivity.

Nature methods 2020 πŸ“Š 116

Intracellular diffusion underlies vital cellular processes. However, it remains difficult to elucidate how an unbound protein diffuses inside the cell with good spatial resolution and...

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Quantitative Analysis of Microscopy Data to Evaluate Bacterial Responses to Antibiotic Treatment.

Methods in molecular biology (Clifton, N.J.) 2023 πŸ“Š 2

Microscopy is a powerful method to evaluate the direct effects of antibiotic action on the single cell level. As with other methodologies, microscopy data is...

d-Serine agonism of GluN1-GluN3 NMDA receptors regulates the activity of enteric neurons and coordinates gut motility.

bioRxiv : the preprint server for biology 2023 πŸ“Š 2

Abstract The enteric nervous system (ENS) is a complex network of diverse molecularly defined classes of neurons embedded in the gastrointestinal wall and responsible for...

Development of hydrogel-based standards and phantoms for non-linear imaging at depth.

Journal of biomedical optics 2023 πŸ“Š 2

SIGNIFICANCE: Rapid advances in medical imaging technology, particularly the development of optical systems with non-linear imaging modalities, are boosting deep tissue imaging. The development of...

Intrafibrillar mineralization of type I collagen with calcium carbonate and strontium carbonate induced by polyelectrolyte-cation complexes.

Nanoscale advances 2024 πŸ“Š 2

Calcium carbonate (CaCO3), possessing excellent biocompatibility, bioactivity, osteoconductivity and superior biodegradability, may serve as an alternative to hydroxyapatite (HAp), the natural inorganic component of bone...

Modulation of Biophysical Properties of Nucleocapsid Protein in the Mutant Spectrum of SARS-CoV-2.

bioRxiv : the preprint server for biology 2024 πŸ“Š 2

Abstract Genetic diversity is a hallmark of RNA viruses and the basis for their evolutionary success. Taking advantage of the uniquely large genomic database of...

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Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues.

bioRxiv : the preprint server for biology 2025 πŸ“Š 2

Abstract DNA-PAINT enables nanoscale imaging with virtually unlimited multiplexing and molecular counting. Here, we address challenges, such as variable imaging performance and target accessibility, that...

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Mechanism of how the universal module XMAP215 Ξ³-TuRC nucleates microtubules.

bioRxiv : the preprint server for biology 2024 πŸ“Š 2

ABSTRACT It has become increasingly evident in recent years that nucleation of microtubules from a diverse set of MTOCs requires both the Ξ³-tubulin ring complex...

πŸ’Ύ Data 🏷️ 1 RRID

Fast and robust drift correction for single-molecule localization microscopy.

Nature communications 2025 πŸ“Š 2

Abstract Owing to its gradual accumulation of molecular positions, single-molecule localization microscopy (SMLM) depends on the proper correction of sample drifts that occur during data...

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Doubling the resolution of light-sheet fluorescence microscopy.

Nature methods 2022 πŸ“Š 2
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