Olympus PlanApo 100Γ—

Olympus PlanApo 100Γ—

Objective β€’ 10 papers

⭐ Foundational

Single-molecule analysis of gene expression using two-color RNA labeling in live yeast.

Nature methods 2013 πŸ“Š 297

Live-cell imaging of mRNA yields important insights into gene expression, but it has generally been limited to the labeling of one RNA species and has...

πŸ’Ύ Data
⭐ Foundational

Stress fibers are generated by two distinct actin assembly mechanisms in motile cells.

The Journal of cell biology 2006 πŸ“Š 833

Stress fibers play a central role in adhesion, motility, and morphogenesis of eukaryotic cells, but the mechanism of how these and other contractile actomyosin structures...

πŸ’Ύ Data

Single-Molecule Fluorescent In Situ Hybridization (smFISH) for RNA Detection in the Fungal Pathogen Candida albicans.

Methods in molecular biology (Clifton, N.J.) 2024 πŸ“Š 2

Candida albicans is the most prevalent human fungal pathogen. Its pathogenicity is linked to the ability of C. albicans to reversibly change morphology and to...

Imaging a target of Ca2+ signalling: dense core granule exocytosis viewed by total internal reflection fluorescence microscopy.

Methods (San Diego, Calif.) 2008 πŸ“Š 24

Ca2+ ions are the most ubiquitous second messenger found in all cells, and play a significant role in controlling regulated secretion from neurons, endocrine, neuroendocrine...

In Situ Characterization of Bak Clusters Responsible for Cell Death Using Single Molecule Localization Microscopy.

Scientific reports 2016 πŸ“Š 31

AbstractApoptosis plays a pivotal role in development and tissue homeostasis in multicellular organisms. Clustering of Bak proteins on the mitochondrial outer membrane is responsible for...

Superfolder mTurquoise2ox optimized for the bacterial periplasm allows high efficiency in vivo FRET of cell division antibiotic targets.

Molecular microbiology 2019 πŸ“Š 39

Summary Fluorescent proteins (FPs) are of vital importance to biomedical research. Many of the currently available fluorescent proteins do not fluoresce when expressed in non‐native...

Chromosome Scaffold is a Double-Stranded Assembly of Scaffold Proteins.

Scientific reports 2015 πŸ“Š 42

AbstractChromosome higher order structure has been an enigma for over a century. The most important structural finding has been the presence of a chromosome scaffold...

⭐ Foundational

Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein.

The Journal of cell biology 2004 πŸ“Š 127

Nudel and Lis1 appear to regulate cytoplasmic dynein in neuronal migration and mitosis through direct interactions. However, whether or not they regulate other functions of...

⭐ Foundational

Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane.

Molecular biology of the cell 2016 πŸ“Š 171

The mechanisms by which the diffusion rate in the plasma membrane (PM) is regulated remain unresolved, despite their importance in spatially regulating the reaction rates...

⭐ Foundational

Endoplasmic reticulum remains continuous and undergoes sheet-to-tubule transformation during cell division in mammalian cells.

The Journal of cell biology 2007 πŸ“Š 250

The endoplasmic reticulum (ER) is a multifaceted cellular organelle both structurally and functionally, and its cell cycle-dependent morphological changes are poorly understood. Our quantitative confocal...

πŸ’Ύ Data

MicroHub Assistant