Bruker Ultima Investigator

Bruker Ultima Investigator

Microscope β€’ 15 papers

Large-volume and deep brain imaging in rabbits and monkeys using COMPACT two-photon microscopy.

Scientific reports 2022 πŸ“Š 2

AbstractIn vivo imaging has been widely used for investigating the structure and function of neurons typically located within ~ 800Β ΞΌm below the cortical surface. Due to light...

Anti-Hebbian plasticity in the motor cortex promotes defensive freezing.

Current biology : CB 2023 πŸ“Š 2

Regional brain activity often decreases from baseline levels in response to external events, but how neurons develop such negative responses is unclear. To study this,...

Identifying lipid particle sub-types in live Caenorhabditis elegans with two-photon fluorescence lifetime imaging.

Frontiers in chemistry 2023 πŸ“Š 3

Fat metabolism is an important modifier of aging and longevity in Caenorhabditis elegans. Given the anatomy and hermaphroditic nature of C. elegans, a major challenge...

ASTRA: a deep learning algorithm for fast semantic segmentation of large-scale astrocytic networks.

bioRxiv : the preprint server for biology 2023 πŸ“Š 3

Abstract Changes in the intracellular calcium concentration are a fundamental fingerprint of astrocytes, the main type of glial cell. Astrocyte calcium signals can be measured...

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Serial intravital 2-photon microscopy and analysis of the kidney using upright microscopes.

Frontiers in physiology 2023 πŸ“Š 4

Serial intravital 2-photon microscopy of the kidney and other abdominal organs is a powerful technique to assess tissue function and structure simultaneously and over time....

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Perinatal Penicillin Exposure Affects Cortical Development and Sensory Processing.

Frontiers in molecular neuroscience 2021 πŸ“Š 7

The prevalent use of antibiotics in pregnant women and neonates raises concerns about long-term risks for children's health, but their effects on the central nervous...

Increased luminal pressure in brain capillaries drives TRPC3-dependent depolarization and constriction of transitional pericytes.

Science signaling 2025 πŸ“Š 7

Cerebral autoregulation ensures constant blood flow, an essential condition of brain health. A fundamental parameter of the brain circulation is the dynamic regulation of microvessel...

Automated Extraction of Skin Wound Healing Biomarkers From In Vivo Label-Free Multiphoton Microscopy Using Convolutional Neural Networks.

Lasers in surgery and medicine 2021 πŸ“Š 8

BACKGROUND AND OBJECTIVES: Histological analysis is a gold standard technique for studying impaired skin wound healing. Label-free multiphoton microscopy (MPM) can provide natural image contrast...

Diverse operant control of different motor cortex populations during learning.

Current biology : CB 2022 πŸ“Š 9

During motor learning,1 as well as during neuroprosthetic learning,2-4 animals learn to control motor cortex activity in order to generate behavior. Two different populations of...

Label-free metabolic biomarkers for assessing valve interstitial cell calcific progression.

Scientific reports 2020 πŸ“Š 9

AbstractCalcific aortic valve disease (CAVD) is the most common form of valve disease where the only available treatment strategy is surgical valve replacement. Technologies for...

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