JEM-1400

JEM-1400

Microscope β€’ 16 papers

πŸ”₯ High Impact

Secretory proteins are delivered to the septin-organized penetration interface during root infection by Verticillium dahliae.

PLoS pathogens 2017 πŸ“Š 82

Successful infection of the host requires secretion of effector proteins to evade or suppress plant immunity. Secretion of effectors in root-infecting fungal pathogens, however, remains...

πŸ’Ύ Data
⭐ Foundational

Mycobacterium tuberculosis replicates within necrotic human macrophages.

The Journal of cell biology 2017 πŸ“Š 134

Mycobacterium tuberculosis modulation of macrophage cell death is a well-documented phenomenon, but its role during bacterial replication is less characterized. In this study, we investigate...

⭐ Foundational

Triggered recruitment of ESCRT machinery promotes endolysosomal repair.

Science (New York, N.Y.) 2018 πŸ“Š 456

A quick fix for leaky endosomes Cells internalize diverse material through various forms of endocytosis into an extensive endolysosomal network. Protecting the integrity of endolysosomal...

πŸ’Ύ Data

Nanotherapy for Cancer and Biological Activities of Green Synthesized AgNPs Using Aqueous Saussurea costus Leaves and Roots Extracts.

Pharmaceuticals (Basel, Switzerland) 2024 πŸ“Š 6

Background/Objectives: Nanoparticles derived from medicinal plants are gaining attention for their diverse biological activities and potential therapeutic applications. Methods: This study explored the antioxidant, anti-inflammatory,...

Effective Penetration of a Liposomal Formulation of Bleomycin through Ex-Vivo Skin Explants from Two Different Species.

Cancers 2022 πŸ“Š 6

Bleomycin is a chemotherapy agent that, when administered systemically, can cause severe pulmonary toxicity. Bleosome is a novel formulation of bleomycin encapsulated in ultra-deformable (UD)...

πŸ”₯ High Impact

The Morphology and Assembly of Respiratory Syncytial Virus Revealed by Cryo-Electron Tomography.

Viruses 2018 πŸ“Š 84

Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract disease in young children. With repeat infections throughout life, it can also...

πŸ’Ύ Data
⭐ Foundational

Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids.

Nature communications 2019 πŸ“Š 122

Abstract Systemic AA amyloidosis is a worldwide occurring protein misfolding disease of humans and animals. It arises from the formation of amyloid fibrils from the...

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⭐ Foundational

Microwave-Assisted Green Synthesis and Antioxidant Activity of Selenium Nanoparticles Using Theobroma Cacao L. Bean Shell Extract.

Molecules (Basel, Switzerland) 2019 πŸ“Š 137

Selenium nanoparticles (SeNPs) are successfully synthesized through microwave heating by using Theobroma cacao L. bean shell extract as a stabilizing and capping agent. Response surface...

⭐ Foundational

Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold.

Science (New York, N.Y.) 2022 πŸ“Š 155

INTRODUCTION The nuclear pore complex (NPC) is the molecular conduit in the nuclear membrane of eukaryotic cells that regulates import and export of biomolecules between...

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⭐ Foundational

Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis.

Nature communications 2019 πŸ“Š 146

AbstractAmyloid fibrils derived from antibody light chains are key pathogenic agents in systemic AL amyloidosis. They can be deposited in multiple organs but cardiac amyloid...

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