Nikon A1

Nikon A1

Microscope β€’ 140 papers

From initial formation to developmental refinement: GABAergic inputs shape neuronal subnetworks in the primary somatosensory cortex.

iScience 2025 πŸ“Š 2

Neuronal subnetworks, also known as ensembles, are functional units formed by interconnected neurons for information processing and encoding in the adult brain. Our study investigates...

πŸ’» Code πŸ’Ύ Data 🏷️ 12 RRIDs

Spatiotemporal Dynamics of Lateral Na+ Diffusion in Apical Dendrites of Mouse CA1 Pyramidal Neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 πŸ“Š 1

Sodium ions (Na + ) are major charge carriers mediating neuronal excitation and play a fundamental role in brain physiology. Glutamatergic synaptic activity is accompanied...

🏷️ 1 RRID

Sin3a Associated Protein 130kDa, sap130, plays an evolutionary conserved role in zebrafish heart development.

bioRxiv : the preprint server for biology 2023

Abstract Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where the left ventricle is reduced in size. A forward genetic screen in mice...

🏷️ 2 RRIDs

Spatial ploidy inference using quantitative imaging.

Cell reports methods 2025

Polyploidy (whole-genome duplication) is a common yet under-surveyed property of tissues across multicellular organisms. Polyploidy plays a critical role during tissue development, following acute stress,...

πŸ’Ύ Data

A scalable long-term in vitro model of human colonic epithelium with continuous barrier function.

bioRxiv : the preprint server for biology 2025

Abstract Background & Aims Human in vitro models of differentiated intestinal epithelium are valuable research tools for discovery and translational medicine. Primary adult colonic epithelium...

πŸ’» Code πŸ’Ύ Data 🏷️ 1 RRID

Uterine collagen deposition fluctuates throughout the estrous cycle and provides a scaffold for gland visualization via the SHG-casting method.

iScience 2025

Uterine extracellular matrix (ECM) and uterine glands are essential parts of the endometrium, with important roles in remodeling associated with the estrous cycle, fertility, and...

πŸ’» Code πŸ’Ύ Data 🏷️ 6 RRIDs

Mutations in the kinesin KIF12 promote MASH in humans and mice by disrupting lipogenic enzyme turnover.

The EMBO journal 2025 πŸ“Š 2

Abstract As a common cause of liver cirrhosis, metabolic dysfunction-associated steatohepatitis (MASH) is regarded as a target of therapeutic intervention. However, a successful therapy has...

πŸ’Ύ Data 🏷️ 15 RRIDs

Long-Term L-Glutamine Treatment Reduces Hemolysis without Ameliorating Hepatic Vaso-Occlusion and Liver Fibrosis in a Mouse Model of Sickle Cell Disease.

Biomedicines 2023 πŸ“Š 3

Sickle cell disease (SCD) is an autosomal recessive monogenic disorder caused by a homozygous mutation in the Ξ²-globin gene, which leads to erythrocyte sickling, hemolysis,...

Plasmon resonance and the imaging of metal-impregnated neurons with the laser scanning confocal microscope.

eLife 2015 πŸ“Š 2

The staining of neurons with silver began in the 1800s, but until now the great resolving power of the laser scanning confocal microscope has not...

πŸ“‹ 8

Modeling stem cell nucleus mechanics using confocal microscopy.

Biomechanics and modeling in mechanobiology 2021 πŸ“Š 2

Nuclear mechanics is emerging as a key component of stem cell function and differentiation. While changes in nuclear structure can be visually imaged with confocal...

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