Tuning the optical and electronic properties of colloidal nanocrystals by lattice strain.
Strain can have a large influence on the properties of materials at the nanoscale. The effect of lattice strain on semiconductor devices has been widely...
Ti
Ti
Microscope • 422 papers
Sensitive red protein calcium indicators for imaging neural activity.
Genetically encoded calcium indicators (GECIs) allow measurement of activity in large populations of neurons and in small neuronal compartments, over times of milliseconds to months....
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The functional diversity of retinal ganglion cells in the mouse.
In the vertebrate visual system, all output of the retina is carried by retinal ganglion cells. Each type encodes distinct visual features in parallel for...
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Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT.
Super-resolution fluorescence microscopy is a powerful tool for biological research, but obtaining multiplexed images for a large number of distinct target species remains challenging. Here...
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Composition and three-dimensional architecture of the dengue virus replication and assembly sites.
Positive-strand RNA viruses are known to rearrange cellular membranes to facilitate viral genome replication. The biogenesis and three-dimensional organization of these membranes and the link...
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Electrical and synaptic integration of glioma into neural circuits.
High-grade gliomas are lethal brain cancers whose progression is robustly regulated by neuronal activity. Activity-regulated release of growth factors promotes glioma growth, but this alone...
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A general method to improve fluorophores for live-cell and single-molecule microscopy.
Specific labeling of biomolecules with bright fluorophores is the keystone of fluorescence microscopy. Genetically encoded self-labeling tag proteins can be coupled to synthetic dyes inside...
Collagen reorganization at the tumor-stromal interface facilitates local invasion.
BACKGROUND: Stromal-epithelial interactions are of particular significance in breast tissue as misregulation of these interactions can promote tumorigenesis and invasion. Moreover, collagen-dense breast tissue increases...
Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators.
Genetically encoded calcium indicators (GECIs) can be used to image activity in defined neuronal populations. However, current GECIs produce inferior signals compared to synthetic indicators...