Microscope • 16 papers
The heterozygous NLGF mouse is considered a mild model of Alzheimer’s disease (AD), closely reflecting the gradual progression observed in humans, compared to more aggressive...
Protein phosphorylation is a ubiquitous post-translational modification that regulates a plethora of intracellular processes, making its analysis crucial for understanding intracellular dynamics. The commonly used...
ABSTRACT Opportunistic colonization and recurring infection by Pseudomonas aeruginosa are substantial risks to lung functionality for people with underlying respiratory diseases such as cystic fibrosis...
3D organoids are vital for biomedical research, offering complex tissue models superior to 2D cultures for studying development, disease, and drug responses. High-throughput imaging of...
The key endosomal regulators Rab5, EEA1, and APPL1 are frequently applied in fluorescence microscopy to mark early endosomes, whereas Rab7 is used as a marker...
Quantitative analysis of biological membrane morphology is essential for understanding fundamental cellular processes such as organelle biogenesis and remodeling. While manual annotation has been the...
From a cohort of 167 infertile patients suffering from multiple morphological abnormalities of the flagellum (MMAF), pathogenic bi-allelic mutations were identified in the CCDC146 gene....
Dataset annotation is a time and labor-intensive task and an integral requirement for training and testing deep learning models. The segmentation of images in life...
AbstractAllodynia is a state in which pain is elicited by innocuous stimuli. Capsaicin applied to the skin results in an allodynia that extends to a...
Abstract Expansion microscopy (ExM) is a highly effective technique for super-resolution fluorescence microscopy that enables imaging of biological samples beyond the diffraction limit with conventional...