Olympus BX63

Olympus BX63

Microscope • 14 papers

🔥 High Impact

Single-molecule live cell imaging of Rep reveals the dynamic interplay between an accessory replicative helicase and the replisome.

Nucleic acids research 2019 📊 65

Abstract DNA replication must cope with nucleoprotein barriers that impair efficient replisome translocation. Biochemical and genetic studies indicate accessory helicases play essential roles in replication...

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⭐ Foundational

Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging.

Nature communications 2017 📊 165

AbstractInvolvement of the immune system in tumour progression is at the forefront of cancer research. Analysis of the tumour immune microenvironment has yielded a wealth...

⭐ Foundational

The evolutionary dynamics of extrachromosomal DNA in human cancers.

Nature genetics 2022 📊 173

AbstractOncogene amplification on extrachromosomal DNA (ecDNA) is a common event, driving aggressive tumor growth, drug resistance and shorter survival. Currently, the impact of nonchromosomal oncogene...

Confocal Laser Scanning MicroscopyDeconvolution MicroscopyFluorescence MicroscopyImmunofluorescence MicroscopyLive Cell ImagingZ-Stack ImagingBX63Leica SP5 ConfocalLeica SP8 ConfocalLSM 880Olympus BX63SP5SP8Zeiss LSM 880 ConfocalFijiImageJLAS XAlexa Fluor 488DAPIEGFPGFPBlockingCell CultureClustered Regularly Interspaced Short Palindromic RepeatsElectroporationFixationFluorescence In Situ HybridizationImmunofluorescenceLentiviralLive ImagingParaformaldehyde FixationPermeabilizationTransfectionHuman Prostate Cancer PC-3Leica SP5 ConfocalLeica SP8 ConfocalOlympus BX63Zeiss LSM 880 ConfocalImageJLAS XBerlin Institute of HealthCalifornia Institute for Regenerative Medicine Center of ExcellenceExperimental and Clinical Research CenterFrancis Crick InstituteGerman Cancer Consortium and German Cancer Research CenterHoward Hughes Medical InstituteJanelia Research CampusMary UniversityMax PlanckMax Planck InstituteMax Planck Institute for Evolutionary BiologyPrinceton UniversityQueen Mary University of Londons Medical Centersen UniversitySt. Anna Children's Cancer Research InstituteStanford UniversitySun Yat-sen UniversityThe Classical AssociationThe State Key Laboratory of BiocontrolUCSDUniversitätsmedizin BerlinUniversity College LondonUniversity College London Cancer InstituteUniversity College London HospitalsUniversity of CaliforniaUniversity of California San DiegoUniversity of California San Diego Light Microscopy Core FacilityUniversity of LondonUniversity of Texas Southwestern Medical CenterUniversity School of MedicineAddgeneBio-RadCorningDakoGibcoPromegaQiagenThermo Fisher ScientificPhotometrics CoolSnap
🏷️ 1 RRID

YeastSAM: A Deep Learning Model for Accurate Segmentation of Budding Yeast Cells.

bioRxiv : the preprint server for biology 2025

Abstract An essential step for quantitative image analysis is cell segmentation, which is the process of defining the outline of individual cells in microscopy images....

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Enkephalinergic Neurons in Barrington’s Nucleus Gate Sex-Specific Control of Micturition.

Research square 2025 📊 1

Abstract Lower urinary tract (LUT) control is a vital physiological function governed by a complex interplay between neural circuits and muscle activity. This regulation depends...

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Regulation of candidalysin underlies Candida albicans persistence in intravascular catheters by modulating NETosis.

PLoS pathogens 2024 📊 3

Candida albicans is a leading cause of intravascular catheter-related infections. The capacity for biofilm formation has been proposed to contribute to the persistence of this...

Network state changes in sensory thalamus represent learned outcomes.

Nature communications 2024 📊 4

Abstract Thalamic brain areas play an important role in adaptive behaviors. Nevertheless, the population dynamics of thalamic relays during learning across sensory modalities remain unknown....

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Parallel pathways carrying direction and orientation selective retinal signals to layer 4 of mouse visual cortex.

bioRxiv : the preprint server for biology 2023 📊 6

Summary Parallel functional and anatomical visual pathways from the retina to primary visual cortex (V1) via the lateral geniculate nucleus (LGN) are common to many...

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Automated quantitative assay of fibrosis characteristics in tuberculosis granulomas.

Frontiers in microbiology 2023 📊 6

INTRODUCTION: Granulomas, the pathological hallmark of Mycobacterium tuberculosis (Mtb) infection, are formed by different cell populations. Across various stages of tuberculosis conditions, most granulomas are...

Parallel pathways carrying direction-and orientation-selective retinal signals to layer 4 of the mouse visual cortex.

Cell reports 2024 📊 8

Parallel visual pathways from the retina to the primary visual cortex (V1) via the lateral geniculate nucleus are common to many mammalian species, including mice,...

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