IX83

IX83

Microscope β€’ 27 papers

πŸ”₯ High Impact

Machine learning metrology of cell confinement in melt electrowritten three-dimensional biomaterial substrates.

Microsystems & nanoengineering 2019 πŸ“Š 84

AbstractTuning cell shape by altering the biophysical properties of biomaterial substrates on which cells operate would provide a potential shape-driven pathway to control cell phenotype....

⭐ Foundational

A tunable refractive index matching medium for live imaging cells, tissues and model organisms.

eLife 2017 πŸ“Š 131

In light microscopy, refractive index mismatches between media and sample cause spherical aberrations that often limit penetration depth and resolution. Optical clearing techniques can alleviate...

πŸ“‹ 17 πŸ’Ύ Data
⭐ Foundational

Recent trends in smartphone-based detection for biomedical applications: a review.

Analytical and bioanalytical chemistry 2021 πŸ“Š 138

Smartphone-based imaging devices (SIDs) have shown to be versatile and have a wide range of biomedical applications. With the increasing demand for high-quality medical services,...

⭐ Foundational

Bright-field holography: cross-modality deep learning enables snapshot 3D imaging with bright-field contrast using a single hologram.

Light, science & applications 2019 πŸ“Š 131

AbstractDigital holographic microscopy enables the 3D reconstruction of volumetric samples from a single-snapshot hologram. However, unlike a conventional bright-field microscopy image, the quality of holographic...

⭐ Foundational

Deciphering the Crosstalk Between Myeloid-Derived Suppressor Cells and Regulatory T Cells in Pancreatic Ductal Adenocarcinoma.

Frontiers in immunology 2019 πŸ“Š 137

Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with rising incidence and a remarkable resistance to current therapies. The reasons for this therapeutic failure include...

⭐ Foundational

Red fluorescent genetically encoded Ca2+ indicators for use in mitochondria and endoplasmic reticulum.

The Biochemical journal 2014 πŸ“Š 140

Ca2+ is a key intermediary in a variety of signalling pathways and undergoes dynamic changes in its cytoplasmic concentration due to release from stores within...

πŸ’Ύ Data
⭐ Foundational

Digital synthesis of histological stains using micro-structured and multiplexed virtual staining of label-free tissue.

Light, science & applications 2020 πŸ“Š 146

AbstractHistological staining is a vital step in diagnosing various diseases and has been used for more than a century to provide contrast in tissue sections,...

πŸ’Ύ Data
⭐ Foundational

High-fidelity structured illumination microscopy by point-spread-function engineering.

Light, science & applications 2021 πŸ“Š 162

AbstractStructured illumination microscopy (SIM) has become a widely used tool for insight into biomedical challenges due to its rapid, long-term, and super-resolution (SR) imaging. However,...

⭐ Foundational

Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin.

Circulation 2021 πŸ“Š 160

Background: SGLT2 (sodium/glucose cotransporter 2) inhibitors exert robust cardioprotective effects against heart failure in patients with diabetes, and there is intense interest to identify the...

⭐ Foundational

Early detection and classification of live bacteria using time-lapse coherent imaging and deep learning.

Light, science & applications 2020 πŸ“Š 166

AbstractEarly identification of pathogenic bacteria in food, water, and bodily fluids is very important and yet challenging, owing to sample complexities and large sample volumes...

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