Microscope • 32 papers
Abstract Super-resolution (SR) 3D rendering allows superior quantitative analysis of intracellular structures but has largely been limited to fixed or ex vivo samples. Here we...
Imaging techniques are widely used to determine the physiological state of bacterial cells and provide an important platform for antibacterial evaluation in biofilms research. The...
The interaction between lamin A and the cytoplasmic skeleton plays a key role in maintaining nuclear mechanical properties. However, the effect of destruction of the...
ABSTRACT Tropomyosin is an important actin cytoskeletal protein underpinning processes such as muscle contraction, cell shape and cell division. Defects in tropomyosin function can lead...
Double-strand break (DSB) repair protein 53BP1 (p53 binding protein-1) mediates long-range DNA end-joining and heterochromatin maintenance. We exploit lattice structured illumination microscopy (SIM) (dual iterative...
Abstract Actin mediates insulin secretion from the pancreatic β-cell through a remodeling process. Previous studies have been hampered by limited resolution, providing an ambiguous depiction...
AbstractMulticellular tumor spheroids embedded in collagen I matrices are common in vitro systems for the study of solid tumors that reflect the physiological environment and...
Abstract The human pathogenic bacteria Bacillus cereus , Bacillus anthracis and the entomopathogenic Bacillus thuringiensis form spores encased in a protein coat surrounded by a...
ABSTRACT Although some budding yeasts have proved tractable and intensely studied models, others are more recalcitrant. Debaryomyces hansenii, an important yeast species in food and...
Density-based clustering is used in many contexts including in single molecule localization microscopy (SMLM), where it is commonly used to elucidate the nanoscale organization of...