LSM 780 Microscopy Papers – Page 2

⭐ Foundational

DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes.

Cell 2017 📊 215

Eukaryotic cells store their chromosomes in a single nucleus. This is important to maintain genomic integrity, as chromosomes packaged into separate nuclei (micronuclei) are prone...

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⭐ Foundational

Direct lysosome-based autophagy of lipid droplets in hepatocytes.

Proceedings of the National Academy of Sciences of the United States of America 2020 📊 216

Hepatocytes metabolize energy-rich cytoplasmic lipid droplets (LDs) in the lysosome-directed process of autophagy. An organelle-selective form of this process (macrolipophagy) results in the engulfment of...

⭐ Foundational

IFITM3 directly engages and shuttles incoming virus particles to lysosomes.

Nature chemical biology 2019 📊 217

Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) have emerged as important innate immune effectors that prevent diverse virus infections in vertebrates. However, the cellular...

Confocal Laser Scanning Microscopy Epifluorescence Microscopy Fluorescence Microscopy Immunofluorescence Microscopy Live Cell Imaging Single-Particle Analysis A1 LSM 780 Nikon A1 Confocal Observer 7 Ti Zeiss LSM 780 Confocal ZEN ZEN Blue Alexa Fluor 488 Alexa Fluor 647 CellMask Cy5 DAPI DiD GFP Hoechst 33342 RFP Rhodamine Texas Red Venus YFP Clustered Regularly Interspaced Short Palindromic Repeats Fixation Immunofluorescence Immunostaining Knockout Live Imaging Paraformaldehyde Fixation Permeabilization Transduction Transfection HeLa (Henrietta Lacks)Human Lung Adenocarcinoma A549 Nikon A1 Confocal Zeiss LSM 780 Confocal ImageJ ZEN ZEN Blue Albert Einstein College of Medicine Einstein College Peking University Rockefeller University University Shenzhen Graduate School Abcam Agilent BD Biosciences Bio-Rad Cell Signaling Technology Corning eBioscience Gibco ibidi Invitrogen Jackson ImmunoResearch Life Technologies MatTek Millipore New England Biolabs Qiagen R&D Systems Roche Santa Cruz Biotechnology Sigma-Aldrich VWR Goat Mouse Rabbit Sheep 40x/1.3 NA 63x/1.4 NA oil

⭐ Foundational

Tissue clearing of both hard and soft tissue organs with the PEGASOS method.

Cell research 2018 📊 331

Tissue clearing technique enables visualization of opaque organs and tissues in 3-dimensions (3-D) by turning tissue transparent. Current tissue clearing methods are restricted by limited...

Confocal Laser Scanning Microscopy Deconvolution Microscopy Fluorescence Microscopy Immunofluorescence Microscopy Light Sheet Fluorescence Microscopy Optical Sectioning Second Harmonic Generation Two-Photon Excitation Microscopy Z-Stack Imaging Leica SP5 Confocal Leica SP8 Confocal LSM 780 LSM 880 SP5 SP8 Zeiss LSM 780 Confocal Zeiss LSM 880 Confocal AutoQuant Excel Fiji GraphPad Prism ImageJ Imaris LAS X Alexa Fluor 488 EdU EGFP FITC GFP tdTomato YFP Blocking Clear Lipid-exchanged Acrylamide-hybridized Rigid Imaging-compatible Tissue-hydrogel Immunofluorescence Immunolabeling-enabled Three-Dimensional Imaging of Solvent-Cleared Organs Paraformaldehyde Fixation Three-Dimensional Imaging of Solvent-Cleared Organs Tissue Clearing Ultimate Three-Dimensional Imaging of Solvent-Cleared Organs Whole Mount Primary Astrocytes Primary Endothelial Cells Leica SP5 Confocal Leica SP8 Confocal Zeiss LSM 780 Confocal Zeiss LSM 880 Confocal AutoQuant Imaris LAS X Excel GraphPad Prism Chinese Academy of Sciences M University National Clinical Research Center Shanghai Institute of Biochemistry and Cell Biology Sichuan University State Key Laboratory of Cell Biology State Key Laboratory of Oral Diseases Texas A&M University University of Chinese Academy of Sciences UT Southwestern Medical Center West China Hospital Abcam Sigma-Aldrich Thermo Fisher Scientific VWR Goat Mouse Rabbit Coherent GaAsP Leica HyD PMT 1x/0.25 NA 25x/0.8 NA 32x/0.85 NA

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⭐ Foundational

Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression.

Nature cell biology 2019 📊 378

Yes-associated protein (YAP) is a transcriptional co-activator that regulates cell proliferation and survival by binding to a select set of enhancers for target gene activation....

Airyscan Microscopy Confocal Laser Scanning Microscopy Fluorescence Recovery After Photobleaching Immunofluorescence Microscopy Lattice Light Sheet Microscopy Light Sheet Fluorescence Microscopy Live Cell Imaging Photoactivated Localization Microscopy Z-Stack Imaging DMi8 Leica DMi8 Leica SP8 Confocal LSM 780 LSM 880 SP8 Zeiss LSM 780 Confocal Zeiss LSM 880 Confocal Escherichia coli ZEN Click-iT EdU EGFP GFP Hoechst 33342 JF549 mCherry Phalloidin RFP Blocking Cell Culture Clustered Regularly Interspaced Short Palindromic Repeats Fixation Immunofluorescence Knockdown Lipofection Live Imaging Paraformaldehyde Fixation Permeabilization Transfection Vibratome Human Embryonic Kidney 293 Human Embryonic Kidney 293T Human Osteosarcoma U2OS Leica DMi8 Leica SP8 Confocal Zeiss LSM 780 Confocal Zeiss LSM 880 Confocal ImageJ Imaris ZEN Eunice Kennedy Shriver National Institute for Child Health and Human Development HHMI Howard Hughes Medical Institute Instituto de Lingüística Janelia Research Campus National Institutes of Health The Classical Association University of California Abcam Addgene Agilent BD Biosciences Cell Signaling Technology Corning Gibco Invitrogen Millipore New England Biolabs Qiagen Sigma-Aldrich Leica HyD Zeiss Airyscan Zeiss Plan-Apochromat 63x

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⭐ Foundational

Single-cell phenotyping within transparent intact tissue through whole-body clearing.

Cell 2014 📊 896

Understanding the structure-function relationships at cellular, circuit, and organ-wide scale requires 3D anatomical and phenotypical maps, currently unavailable for many organs across species. At the...

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⭐ Foundational

Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy.

Nature communications 2017 📊 278

AbstractSubunit vaccines have been investigated in over 1000 clinical trials of cancer immunotherapy, but have shown limited efficacy. Nanovaccines may improve efficacy but have rarely...

3D Imaging Atomic Force Microscopy Confocal Laser Scanning Microscopy Deconvolution Microscopy Fluorescence Microscopy Light Sheet Fluorescence Microscopy Structured Illumination Microscopy Super-Resolution Microscopy Transmission Electron Microscopy Leica SP8 Leica SP8 Confocal Lightsheet Z.1 LSM 780 SP8 Ti Zeiss Lightsheet Z.1 Light Sheet Zeiss LSM 780 Zeiss LSM 780 Confocal GraphPad Prism LAS X APC APC-Cy7 BV421 Cy5 Cy5.5 Cy7 DAPI FITC Hoechst 33342 LysoTracker LysoTracker Green LysoTracker Red PE PE-Cy5 PerCP Cell Culture Clear Lipid-exchanged Acrylamide-hybridized Rigid Imaging-compatible Tissue-hydrogel Co-culture Fixation Lipofection Paraformaldehyde Fixation Passive CLARITY Technique Permeabilization Tissue Clearing Transfection Mouse Macrophage RAW 264.7 Mouse Melanoma B16 Primary Macrophages Primary Natural Killer Cells Primary T Cells Leica SP8 Confocal Zeiss Lightsheet Z.1 Light Sheet Zeiss LSM 780 Confocal LAS X GraphPad Prism China Pharmaceutical University Ministry of Defence National Institutes of Health NIH Pharmaceutical University State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics The Classical Association University of Southern California Vaccine Research Center Xiamen University BD Biosciences BioLegend eBioscience Invitrogen Life Technologies Sigma-Aldrich Thermo Fisher Scientific

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Capsaicin-Induced Endocytosis of Endogenous Presynaptic CaV2.2 in DRG-Spinal Cord Co-Cultures Inhibits Presynaptic Function.

Function (Oxford, England) 2023 📊 6

Abstract The N-type calcium channel, CaV2.2 is key to neurotransmission from the primary afferent terminals of dorsal root ganglion (DRG) neurons to their postsynaptic targets...

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Calcium Dobesilate (CaD) Attenuates High Glucose and High Lipid-Induced Impairment of Sarcoplasmic Reticulum Calcium Handling in Cardiomyocytes.

Frontiers in cardiovascular medicine 2021 📊 6

Calcium dobesilate (CaD) is used effectively in patients with diabetic microvascular disorder, retinopathy, and nephropathy. Here we sought to determine whether it has an effect...

Confocal Laser Scanning Microscopy LSM 780 Fluo-4 LSM 780 Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University Hospital Conde S. Januário Shenzhen Children's Hospital Shenzhen University University of Alabama at Birmingham Merck Sigma-Aldrich Thermo Fisher Thermo Fisher Scientific

⭐ Foundational

Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex.

Neuron 2017 📊 358

The successful planning and execution of adaptive behaviors in mammals may require long-range coordination of neural networks throughout cerebral cortex. The neuronal implementation of signals...

Calcium Imaging Confocal Laser Scanning Microscopy Deconvolution Microscopy Optogenetics Two-Photon Excitation Microscopy Bruker Ultima Investigator Multiphoton Leica SP5 Confocal LSM 780 SP5 Zeiss LSM 780 Zeiss LSM 780 Confocal Caenorhabditis elegans Fiji ImageJ LAS X MATLAB Cy3 DAPI DiD DiO EdU EGFP EYFP GCaMP GCaMP6f GFP mCherry RCaMP YFP Adeno-Associated Virus Fixation Immunohistochemistry Immunostaining Paraformaldehyde Fixation Transfection Vibratome Human Embryonic Kidney 293 Bruker Ultima Investigator Multiphoton Leica SP5 Confocal Zeiss LSM 780 Confocal ImageJ LAS X MATLAB California Institute of Technology Howard Hughes Medical Institute Stanford University Abcam Jackson ImmunoResearch Santa Cruz Biotechnology Sigma-Aldrich Chicken Donkey Rabbit Hamamatsu Orca Flash 4.0 PCO sCMOS Pco.edge 5.5 sCMOS 2x/0.14 NA Olympus 25x/1.05 NA Hamamatsu FF01-520 Nikon FF495-Di03 Photometrics FF01-520 Photometrics FF02-617 Photometrics FF555-Di03 Semrock Di01-50 Semrock FF01-520 Semrock FF01-560 Semrock FF02-617 Semrock FF410/504 Semrock FF495-Di03 Semrock FF520-Di02 Semrock FF555-Di03

💾 Data 🏷️ 5 RRIDs

LSM 780

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